Current Advances in Computational biology of Lung Cancer.

Current Advances in Computational biology of Lung Cancer.

Purbasha Pati; Pooja Kumari; Neha Kumari; Kumari Surekha Mahto; Shekhar Marandi; Sadaf Naaz; Sweety Guria Rani; Naiyar Naaz; Rupa Verma; Saurabh Kumar Gupta; Mukesh Nitin

International Journal of Current Science Research and Review vol.(50) isssue1 (2022)

Abstract :

Lung cancer is the main basis of cancer death amongst men and women, making up almost 25% of the world’s total cancer deaths. Lung cancer described for nearly 1.6 million deaths in 2012 and 1.80 million deaths in 2020. Small cell lung cancer and non-small-cell lung cancer are the two key categories of Lung cancer. The signs of lung cancer include hemoptysis, weight loss, shortness of breath and chest pain. Lung cancer treated by chemotherapy, surgery and CT scan. In this review paper, one of the most crucial zones aiming lung cancer diagnosis has been discussed. Computer-aided diagnosis (CAD) systems adapted for lung cancer can increase the patients’ survival chances. A typical CAD system for lung cancer functions in the fields of lung segmentation, detecting lung nodules and the diagnosis of the nodules as benign or malignant. CAD systems for lung cancer are examined in a huge number of research case studies. CAD system steps and outlining of inhibitor genes at molecular level is being discussed. An insight into multi-omics and molecular dynamics simulations is also given in this paper.