Are you a passionate researcher ready to push the boundaries of neuro-oncology and glioblastoma therapy? The prestigious Hamerlik Lab at the University of Manchester is inviting applications for a Research Associate role focused on translational research in brain cancer. This is your opportunity to contribute to cutting-edge cancer biology, using innovative patient-derived models and working alongside world-leading scientists.
📍 Location: Paterson Research Building, Manchester
🧪 Department: Cancer Sciences, Faculty of Biology, Medicine & Health
📆 Application Deadline: [Insert Closing Date]
📧 Contact: Prof. Petra Hamerlik – petra.hamerlik@manchester.ac.uk
🧬 About the Role
As a Research Associate in Translational Neuro-Oncology, you will be at the forefront of a multidisciplinary investigation into the genomic instability of glioblastoma (GBM). Your focus will be on uncovering the molecular mechanisms driving aberrant DNA repair and its interaction with DNA replication and transcription.
Using advanced functional assays, molecular biology techniques, and unique patient-derived spheroid and xenograft models developed in-house, this project aims to lay the groundwork for proof-of-mechanism studies that can lead to breakthrough therapies for one of the most aggressive brain cancers.
🔍 Key Responsibilities
- Conduct high-level research on DNA damage repair, transcriptional interference, and tumor cell replication dynamics in GBM
- Utilize and expand patient-derived 3D glioblastoma models and xenografts
- Plan and execute laboratory experiments independently
- Analyze, interpret, and present research findings
- Contribute to peer-reviewed publications and national/international conferences
- Collaborate across departments and with external academic and clinical partners
🎓 Qualifications & Skills
- PhD (or equivalent) in biology, molecular oncology, or a related field
- Demonstrated experience in molecular and cellular biology, cancer biology, or tumor modeling
- Proven ability to lead experimental design and data analysis
- Strong communication skills and a collaborative mindset
- A publication track record in relevant fields is desirable
🌍 Why Choose the University of Manchester?
As a global leader in research and innovation, the University of Manchester offers exceptional opportunities for career growth, collaboration, and impact. Our Faculty of Biology, Medicine and Health is home to world-renowned experts and groundbreaking projects in oncology, neuroscience, and translational medicine.
💡 What You’ll Get in Return
- 💰 Competitive salary and benefits
- 🏖️ Generous annual leave plus paid university closure during holidays
- 👨⚕️ Access to health and wellbeing services, including EAP
- 🧓 Market-leading pension scheme
- 🌐 Hybrid and flexible working arrangements considered
- 🎓 A nurturing research environment with training opportunities and career development support
- 🚺 Commitment to gender equality via the Athena SWAN Silver Award
“We particularly encourage applications from women and individuals from underrepresented backgrounds in science.”
📩 Ready to Apply?
Applications are open until [Insert Deadline]. Be part of the next breakthrough in glioblastoma research.
🔗 Apply now via the University of Manchester Careers Portal
📧 For informal inquiries: Prof. Petra Hamerlik at petra.hamerlik@manchester.ac.uk
📑 Further particulars and person specification available on the job listing page.
Note: Recruitment agencies, please be advised that unsolicited CVs will not be considered.
🧠 Final Thoughts
If you’re driven by scientific curiosity and determined to impact the future of neuro-oncology, this is your opportunity to join one of the UK’s top research environments. Help uncover the genetic secrets of glioblastoma and shape therapies that matter.
🔬 Fuel your research. Empower your impact. Apply today